(function ($) { "use strict"; var $window = $(window); function debounce(func, wait, immediate) { var timeout; return function () { var context = this, args = arguments; var later = function () { timeout = null; if (!immediate) func.apply(context, args); }; var callNow = immediate && !timeout; clearTimeout(timeout); timeout = setTimeout(later, wait); if (callNow) func.apply(context, args); }; } function rtl_slick() { if ($("body").hasClass("rtl")) { return true; } else { return false; } } $window.on("elementor/frontend/init", function () { var ModuleHandler = elementorModules.frontend.handlers.Base; var PostMarquee = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.wrapper = this.$element.find(".elespare-flash-wrap"); this.run(); }, getDefaultSettings: function () { var pauseticker = false; if (this.getElementSettings("_pause_on_hover") == "yes") { pauseticker = true; } return { //duration in milliseconds of the marquee speed: this.getElementSettings("_animation_speed"), //gap in pixels between the tickers gap: 0, //time in milliseconds before the marquee will start animating delayBeforeStart: 0, //'left' or 'right' // direction: 'right', //true or false - should the marquee be duplicated to show an effect of continues flow duplicated: true, pauseOnHover: pauseticker, startVisible: true, }; }, getDefaultElements: function () { return { $container: this.findElement(this.getSettings("container")), }; }, run: function () { var filter_wrap = this.wrapper.find(".marquee.elespare-flash-side"); filter_wrap.marquee(this.getDefaultSettings()); }, }); var PostCarousel = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.run(); }, getDefaultSettings: function () { return { autoplay: false, arrows: false, checkVisible: false, container: ".elespare-posts-wrap", dots: false, infinite: true, rows: 0, slidesToShow: 3, prevArrow: $("
") .append(this.findElement(".slick-prev").clone().show()) .html(), nextArrow: $("
") .append(this.findElement(".slick-next").clone().show()) .html(), }; }, getDefaultElements: function () { return { $container: this.findElement(this.getSettings("container")), }; }, onElementChange: debounce(function () { this.elements.$container.slick("unslick"); this.run(); }, 200), getSlickSettings: function () { var autoplaycarousel = false; if (this.getElementSettings("autoplay") == "yes") { autoplaycarousel = true; } var settings = { infinite: !!this.getElementSettings("loop"), autoplay: autoplaycarousel, autoplaySpeed: this.getElementSettings("autoplay_speed"), speed: this.getElementSettings("animation_speed"), centerMode: !!this.getElementSettings("center"), slidesToScroll: 1, rtl: rtl_slick(), }; switch (this.getElementSettings("navigation")) { case "arrow": settings.arrows = true; break; case "dots": settings.dots = true; break; case "both": settings.arrows = true; settings.dots = true; break; } // var blockname = this.elements.$container.attr('data-blockname'); settings.slidesToShow = parseInt(this.getElementSettings("slides_to_show")) || 1; settings.slidesToShow = parseInt(this.getElementSettings("slides_to_show")) || 1; settings.responsive = [ { breakpoint: elementorFrontend.config.breakpoints.lg, settings: { slidesToShow: parseInt(this.getElementSettings("slides_to_show_tablet")) || settings.slidesToShow, }, }, { breakpoint: elementorFrontend.config.breakpoints.md, settings: { slidesToShow: parseInt(this.getElementSettings("slides_to_show_mobile")) || parseInt(this.getElementSettings("slides_to_show_tablet")) || settings.slidesToShow, }, }, ]; return $.extend({}, this.getSettings(), settings); }, run: function () { this.elements.$container .not(".slick-initialized") .slick(this.getSlickSettings()); }, }); //Masonry var PostMasonry = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.run(); }, getLayoutMode: function () { var layout = "even"; return layout === "even" ? "masonry" : layout; }, getDefaultSettings: function () { return { itemSelector: ".elespare-posts-masonry-item-wrapper", percentPosition: true, layoutMode: this.getLayoutMode(), }; }, getDefaultElements: function () { return { $container: this.findElement(".elespare-isotope"), }; }, run: function () { var self = this; self.elements.$container.isotope(self.getDefaultSettings()); }, }); //------- var MainBannerOne = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.run(); }, getDefaultSettings: function () { return { autoplay: true, arrows: true, checkVisible: false, container: ".elespare-carousel-wrap", dots: false, infinite: true, rows: 0, slidesToShow: 1, prevArrow: $("
") .append(this.findElement(".slick-prev").clone().show()) .html(), nextArrow: $("
") .append(this.findElement(".slick-next").clone().show()) .html(), }; }, getDefaultElements: function () { return { $container: this.findElement(this.getSettings("container")), }; }, onElementChange: debounce(function () { this.elements.$container.slick("unslick"); this.run(); }, 200), getSlickSettings: function () { var autoplaybanner = false; if (this.getElementSettings("_autoplay") == "yes") { autoplaybanner = true; } var bannersettings = { infinite: !!this.getElementSettings("_loop"), autoplay: autoplaybanner, autoplaySpeed: this.getElementSettings("_autoplay_speed"), speed: this.getElementSettings("_animation_speed"), slidesToScroll: 1, rtl: rtl_slick(), }; bannersettings.slidesToShow = parseInt(this.elements.$container.attr("data-num")) || 1; bannersettings.responsive = [ { breakpoint: elementorFrontend.config.breakpoints.lg, settings: { slidesToShow: 1, }, }, { breakpoint: elementorFrontend.config.breakpoints.md, settings: { slidesToShow: 1, }, }, ]; return $.extend({}, this.getSettings(), bannersettings); }, run: function () { this.elements.$container .not(".slick-initialized") .slick(this.getSlickSettings()); }, }); var MainBannerTwo = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.run(); }, getDefaultSettings: function () { return { autoplay: true, arrows: true, checkVisible: false, container: ".elespare-carousel-wrap", dots: false, infinite: true, rows: 0, slidesToShow: 1, prevArrow: $("
") .append(this.findElement(".slick-prev").clone().show()) .html(), nextArrow: $("
") .append(this.findElement(".slick-next").clone().show()) .html(), }; }, getDefaultElements: function () { return { $container: this.findElement(this.getSettings("container")), }; }, onElementChange: debounce(function () { this.elements.$container.slick("unslick"); this.run(); }, 200), getSlickSettings: function () { var autoplaybanner = false; if (this.getElementSettings("_autoplay") == "yes") { autoplaybanner = true; } var bannersettings = { infinite: !!this.getElementSettings("_loop"), autoplay: autoplaybanner, autoplaySpeed: this.getElementSettings("_autoplay_speed"), speed: this.getElementSettings("_animation_speed"), slidesToScroll: 1, rtl: rtl_slick(), }; bannersettings.slidesToShow = parseInt(this.elements.$container.attr("data-num")) || 1; bannersettings.responsive = [ { breakpoint: elementorFrontend.config.breakpoints.lg, settings: { slidesToShow: 1, }, }, { breakpoint: elementorFrontend.config.breakpoints.md, settings: { slidesToShow: 1, }, }, ]; return $.extend({}, this.getSettings(), bannersettings); }, run: function () { this.elements.$container .not(".slick-initialized") .slick(this.getSlickSettings()); }, }); //----- //Post banner slider var PostBannerCarousel = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.run(); }, getDefaultSettings: function () { return { autoplay: true, arrows: true, checkVisible: false, container: ".elespare-carousel-wrap", dots: false, infinite: true, rows: 0, slidesToShow: 1, prevArrow: $("
") .append(this.findElement(".slick-prev").clone().show()) .html(), nextArrow: $("
") .append(this.findElement(".slick-next").clone().show()) .html(), }; }, getDefaultElements: function () { return { $container: this.findElement(this.getSettings("container")), }; }, onElementChange: debounce(function () { this.elements.$container.slick("unslick"); this.run(); }, 200), getSlickSettings: function () { var autoplaybanner = false; if (this.getElementSettings("_autoplay") == "yes") { autoplaybanner = true; } var bannersettings = { infinite: !!this.getElementSettings("_loop"), autoplay: autoplaybanner, autoplaySpeed: this.getElementSettings("_autoplay_speed"), speed: this.getElementSettings("_animation_speed"), slidesToScroll: 1, rtl: rtl_slick(), }; var parent_class = this.elements.$container.parents(".elementor-column"); var admin_attr = parent_class.attr("data-col"); if ( admin_attr <= 33 || parent_class.hasClass("elementor-col-33") || parent_class.hasClass("elementor-col-20") || parent_class.hasClass("elementor-col-16") ) { bannersettings.slidesToShow = 1; } else { bannersettings.slidesToShow = parseInt(this.elements.$container.attr("data-num")) || 1; } bannersettings.responsive = [ { breakpoint: elementorFrontend.config.breakpoints.lg, settings: { slidesToShow: 1, }, }, { breakpoint: elementorFrontend.config.breakpoints.md, settings: { slidesToShow: 1, }, }, ]; return $.extend({}, this.getSettings(), bannersettings); }, run: function () { this.elements.$container .not(".slick-initialized") .slick(this.getSlickSettings()); }, }); var PostBannerTrendings = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.run(); }, getDefaultSettings: function () { return { autoplay: true, arrows: false, checkVisible: false, container: ".elespare-trending-wrap", dots: false, infinite: true, vertical: true, verticalSwiping: true, rows: 0, slidesToShow: 3, }; }, getDefaultElements: function () { return { $container: this.findElement(this.getSettings("container")), }; }, onElementChange: debounce(function () { this.elements.$container.slick("unslick"); this.run(); }, 200), getSlickSettings: function () { var slide_to_show = this.getElementSettings("trending_slides_to_show"); var parent_class = this.elements.$container.parents(".elementor-element"); var widget_name = parent_class .find(".elementor-widget-main-banner-1") .attr("data-widget_type"); var widget_name_banner_2 = parent_class .find(".elementor-widget-main-banner-2") .attr("data-widget_type"); var verticals = true; var admin_attr = parent_class.attr("data-col"); if ( widget_name == "main-banner-1.default" || widget_name_banner_2 == "main-banner-2.default" ) { if (admin_attr == "66" || parent_class.hasClass("elementor-col-66")) { verticals = false; slide_to_show = 2; } else if ( admin_attr == "50" || parent_class.hasClass("elementor-col-50") ) { verticals = false; slide_to_show = 2; } else if ( admin_attr == "33" || parent_class.hasClass("elementor-col-33") ) { verticals = false; slide_to_show = 1; } else if ( admin_attr == "25" || parent_class.hasClass("elementor-col-25") ) { verticals = false; slide_to_show = 1; } else { verticals = false; slide_to_show = this.getElementSettings("trending_slides_to_show"); } } else { verticals = false; } var autoplayverticale = false; if (this.getElementSettings("trending_autoplay") == "yes") { autoplayverticale = true; } var verticalsettings = { infinite: !!this.getElementSettings("trending_loop"), autoplay: autoplayverticale, autoplaySpeed: this.getElementSettings("trending_autoplay_speed"), speed: this.getElementSettings("trending_animation_speed"), slidesToShow: slide_to_show, slidesToScroll: 1, vertical: verticals, rtl: rtl_slick(), }; verticalsettings.responsive = [ { breakpoint: elementorFrontend.config.breakpoints.lg, settings: { slidesToShow: parseInt( this.getElementSettings("trending_slides_to_show_tablet") ) || verticalsettings.slidesToShow, vertical: false, }, }, { breakpoint: elementorFrontend.config.breakpoints.md, settings: { slidesToShow: parseInt( this.getElementSettings("trending_slides_to_show_mobile") ) || parseInt(this.getElementSettings("slides_to_show_tablet")) || verticalsettings.slidesToShow, vertical: false, }, }, ]; return $.extend({}, this.getSettings(), verticalsettings); }, run: function () { this.elements.$container .not(".slick-initialized") .slick(this.getSlickSettings()); }, }); var PostBannerVerticaleTrendings = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.run(); }, getDefaultSettings: function () { return { autoplay: true, arrows: false, checkVisible: false, container: ".elespare-trending-wrap", dots: false, infinite: true, vertical: true, verticalSwiping: true, rows: 0, slidesToShow: 3, }; }, getDefaultElements: function () { return { $container: this.findElement(this.getSettings("container")), }; }, onElementChange: debounce(function () { this.elements.$container.slick("unslick"); this.run(); }, 200), getSlickSettings: function () { var slide_to_show = 3; var autoplayverticale = false; if (this.getElementSettings("trending_autoplay") == "yes") { autoplayverticale = true; } var parent_class = this.elements.$container.parents( ".elementor-element.elementor-widget-post-banner" ); var widget_name = parent_class.attr("data-widget_type"); if (widget_name == "post-banner.default") { if ( parent_class .find(".elespare-banner-one-wrap") .hasClass("banner-style-4") || parent_class .find(".elespare-banner-one-wrap") .hasClass("banner-style-5") || parent_class .find(".elespare-banner-one-wrap") .hasClass("banner-style-6") ) { slide_to_show = 4; } } var verticalsettings = { infinite: !!this.getElementSettings("trending_loop"), autoplay: autoplayverticale, autoplaySpeed: this.getElementSettings("trending_autoplay_speed"), speed: this.getElementSettings("trending_animation_speed"), slidesToShow: slide_to_show, slidesToScroll: 1, vertical: true, verticalSwiping: true, // rtl: rtl_slick() }; verticalsettings.responsive = [ { breakpoint: elementorFrontend.config.breakpoints.lg, settings: { slidesToShow: 2, vertical: false, verticalSwiping: false, rtl: rtl_slick(), }, }, { breakpoint: elementorFrontend.config.breakpoints.md, settings: { slidesToShow: 1, vertical: false, verticalSwiping: false, rtl: rtl_slick(), }, }, ]; return $.extend({}, this.getSettings(), verticalsettings); }, run: function () { this.elements.$container .not(".slick-initialized") .slick(this.getSlickSettings()); }, }); //Post Trending Carousel var PostTrendingsCarousel = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.run(); }, getDefaultSettings: function () { return { autoplay: false, arrows: false, checkVisible: false, container: ".elespare-trending-wrap", dots: false, infinite: true, vertical: false, verticalSwiping: false, rows: 0, slidesToShow: 3, }; }, getDefaultElements: function () { return { $container: this.findElement(this.getSettings("container")), }; }, onElementChange: debounce(function () { this.elements.$container.slick("unslick"); this.run(); }, 200), getSlickSettings: function () { var verticals = false; var slide_to_show = 3; var parent_class = this.elements.$container.parents(".elementor-column"); var rtl = rtl_slick(); var admin_attr = parent_class.attr("data-col"); if (parent_class.hasClass("elementor-col-66")) { verticals = false; slide_to_show = 2; rtl = rtl_slick(); } if (parent_class.hasClass("elementor-col-50")) { verticals = false; slide_to_show = 2; rtl = rtl_slick(); } if (parent_class.hasClass("elementor-col-33")) { verticals = true; slide_to_show = 5; rtl = false; } if (parent_class.hasClass("elementor-col-25")) { verticals = true; slide_to_show = 2; rtl = false; } if (parent_class.hasClass("elementor-col-16")) { verticals = true; slide_to_show = 2; rtl = false; } if (admin_attr == "66") { verticals = false; slide_to_show = 2; rtl = rtl_slick(); } if (admin_attr == "50") { verticals = false; slide_to_show = 2; rtl = rtl_slick(); } if (admin_attr == "33") { verticals = true; slide_to_show = 5; rtl = false; } if (admin_attr == "25") { verticals = true; slide_to_show = 2; rtl = false; } if (admin_attr == "16") { verticals = true; slide_to_show = 2; rtl = false; } var verticalsettings = { infinite: !!this.getElementSettings("trending_loop"), autoplay: !!this.getElementSettings("trending_autoplay"), autoplaySpeed: this.getElementSettings("trending_autoplay_speed"), speed: this.getElementSettings("trending_animation_speed"), slidesToShow: slide_to_show, slidesToScroll: 1, vertical: verticals, rtl: rtl, }; verticalsettings.responsive = [ { breakpoint: elementorFrontend.config.breakpoints.lg, settings: { slidesToShow: 2, vertical: false, verticalSwiping: false, rtl: rtl_slick(), }, }, { breakpoint: elementorFrontend.config.breakpoints.md, settings: { slidesToShow: 5, vertical: true, verticalSwiping: true, rtl: false, }, }, ]; return $.extend({}, this.getSettings(), verticalsettings); }, run: function () { this.elements.$container .not(".slick-initialized") .slick(this.getSlickSettings()); }, }); //Tabs var PostTab = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.wrapper = this.$element.find(".elespare-post-tab"); this.run(); }, run: function () { var filter_wrap = this.wrapper.find(".elespare-post-tab-filter"), filter = filter_wrap.find("li"), event = this.wrapper.data("event"), args = this.wrapper.data("query-args"); filter.on( event, debounce(function (e) { e.preventDefault(); var $self = $(this), term_id = $self.data("term"), $wrapper = $self.closest(".elespare-post-tab"), content = $wrapper.find(".elespare-post-tab-content"), loading = content.find(".elespare-post-tab-loading"), tab_item = content.find(".elespare-post-tab-item-wrapper"), $content_exist = false; if (0 === loading.length) { filter.removeClass("active"); tab_item.removeClass("active"); $self.addClass("active"); tab_item.each(function () { var $self = $(this), $content_id = $self.data("term"); if (term_id === $content_id) { $self.addClass("active"), ($content_exist = true); } }); if (false === $content_exist) { $.ajax({ url: ElespareLocalize.ajax_url, type: "POST", data: { action: "elespare_post_tab_action", security: ElespareLocalize.nonce, post_tab_query: args, term_id: term_id, }, beforeSend: function () { content.append( '' ); }, success: function (response) { content.find(".elespare-post-tab-loading").remove(); content.append(response); }, error: function (error) {}, }); } } }, 200) ); }, }); var SearchForm = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.wrapper = this.$element.find(".elespare-search-wrapper"); this.run(); }, run: function () { var searchContainer = this.wrapper.find(".elespare-search--toggle"); var btn = this.wrapper.find(".elespare-search-icon--toggle"); var close = this.wrapper.find(".elespare--site-search-close"); var dropdown_click = this.wrapper.find( ".elespare-search-dropdown-toggle" ); btn.on("click", function () { searchContainer.addClass("show"); dropdown_click.toggleClass("show"); }); close.on("click", function () { searchContainer.removeClass("show"); }); const $menu = this.wrapper.find(".elespare-search-dropdown-toggle"); $(document).mouseup((e) => { if ( !$menu.is(e.target) && // if the target of the click isn't the container... $menu.has(e.target).length === 0 ) { // ... nor a descendant of the container $menu.removeClass("show"); } }); $(document).on("keydown", function (e) { if (e.keyCode === 27) { // ESC searchContainer.removeClass("show"); } }); }, }); var NavMenu = ModuleHandler.extend({ onInit: function () { ModuleHandler.prototype.onInit.apply(this, arguments); this.wrapper = this.$element.find(".elespare-navigation-wrapper"); this.run(); }, run: function () { var toggle = this.wrapper.find(".elespare-menu-toggle"); var nav = this.wrapper.find(".elespare-moblie-ham-menu"); var overlay = this.wrapper.find(".elespare-overlay"); var close = this.wrapper.find(".elespare--close-menu-side-bar"); var main = this.wrapper.find(".elespare-main-navigation"); var desktop_subnav = main.find("ul >.menu-item-has-children>a"); var sub = main.find(".sub-menu"); if ( this.wrapper.hasClass("vertical") || this.wrapper.hasClass("horizontal") ) { sub.each(function (index) { $(this).wrap('
'); }); } sub .parents("li") .find("> a") .append('

Revolutionizing Digital Trials: The Emergence of Interactive Gaming in Clinical Research

In the rapidly evolving landscape of clinical research, technology-driven approaches are transforming how trials are designed, conducted, and experienced. Among the latest innovations is the integration of interactive digital games, which serve as powerful tools to enhance participant engagement, improve data integrity, and streamline trial processes. This convergence of gaming and healthcare is not merely a trend but a strategic response to longstanding challenges in clinical studies, particularly in maintaining participant adherence and ensuring accurate data collection.

The Rise of Gamification in Clinical Trials

Historically, clinical trials have faced obstacles such as high dropout rates, low participant engagement, and inconsistent data reporting. According to a 2022 report by Pharma Intelligence, participant dropout can reach up to 30% in certain long-term studies, significantly impacting the reliability and cost-effectiveness of trials.

To address these issues, industry leaders are exploring gamification—implementing game mechanics and interactive elements into trial protocols. This approach harnesses human motivation, competitive instincts, and entertainment value to foster sustained participation. An exemplary case is the use of digital platforms that incorporate real-time feedback, rewards, and immersive narratives to keep participants motivated and compliant with study requirements.

Case Study: The Genesis of Interactive Digital Trials

One pioneering example of this paradigm shift is the development of the Orb Trials game. This platform exemplifies how interactive gaming mechanics can be integrated into clinical trial processes, transforming passive observation into active participation.

Orb Trials offers a virtual environment where participants engage in tasks that mirror real-world data collection activities, all within an engaging, game-like interface. This isn’t just about making trials more entertaining; it’s about creating scientifically validated frameworks that leverage game design to improve adherence to protocols and capture high-quality data.

Key Features of Innovative Digital Trials
Feature Description Impact
Real-Time Engagement Interactive activities that respond dynamically to participant input. Increases adherence; reduces dropout rates.
Personalized Feedback Tailored notifications and progress updates based on participant performance. Enhances motivation and compliance.
Data Validation & Integrity Built-in mechanisms to cross-verify data through in-game checkpoints. Boosts reliability of collected data.
Remote Accessibility Accessible across devices, enabling participation from anywhere. Facilitates broader recruitment and inclusivity.

Industry Insights: The Scientific Validation of Gamified Trials

Recent peer-reviewed studies point to the tangible benefits of integrating gaming elements into clinical research. A 2021 study published in Nature Communications demonstrated that digital gamification increased participant adherence by up to 40% compared to traditional methods. Moreover, gamified interventions showed promising results in neurodegenerative disease studies, where cognitive engagement plays a vital role.

«The fusion of gaming and clinical research could serve as a catalyst in transforming trial methodologies—making them more participant-centric and data-driven.» — Dr. Isabelle Martin, Chief Scientific Officer at BioInnovate.

Strategic Implications and Future Outlook

The integration of tools like the Orb Trials game indicates a strategic shift towards more immersive, participant-friendly trial environments. As regulatory agencies increasingly endorse digital health technologies, the landscape is poised for accelerated adoption of gamified solutions.

Furthermore, advances in artificial intelligence and machine learning are expected to enhance these platforms with adaptive algorithms that customize experiences, predict adherence issues before they arise, and refine data collection strategies in real time.

The Bottom Line: Innovation Meets Ethics and Validation

While technological innovation bolsters the potential for revolutionizing clinical trials, rigorous validation and adherence to ethical standards remain paramount. The credibility of gamified platforms hinges on demonstrable benefits supported by scientific evidence, compliance with privacy laws, and transparent data management practices.

Platforms like Orb Trials game exemplify how digital tools can be seamlessly integrated into rigorous clinical research frameworks—bringing enhanced engagement without compromising scientific integrity.

Conclusion

As the field of clinical research evolves, the strategic adoption of gamification and digital engagement tools like the Orb Trials game offers a compelling pathway to more efficient, participant-centered studies. By grounding these innovations in scientific validation and ethical rigor, industry leaders can pave the way for a future where clinical trials are not only more effective but also more humane and accessible.

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